fibrin
/ˈfʌɪbrɪn
/ /ˈfɪbrɪn/noun [mass noun] Biochemistry
An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed....
- In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
- It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.
Derivatives
fibrinoid
- In addition, three patients had hyaline collagen degeneration, four myxoid degeneration, three fibrinoid degeneration, and six had mixed lesions.
- Fibrin deposition was found in areas of fibrinoid necrosis within the glomeruli and in the interstitium.
- Other nonspecific features include intimal proliferation, duplication and/or fragmentation of the internal elastic lamina, a sparse perivascular inflammatory infiltrate, and fibrinoid necrosis of the intima.
fibrinous
/ /ˈfɪbrɪnəs / adjective ...- This progressive process involves alterations in fibrin turnover, which leads to the formation of fibrinous deposits and membranes with sequestration of infected fluid.
- Upon review of the slides, we observed a fragment of bladder mucosa with dilated vascular spaces, hemorrhage, acute inflammation, fibrinous exudate, and focal fibrosis in the lamina propria.
- Because the heart is constricted by fluid or a rigid fibrinous or calcified pericardium, negative intrathoracic pressure during inspiration is not transmitted to the pericardial sac.
Origin
Early 19th century: from fibre + -in1.