enrage, infuriate, anger, madden, send into a rage, outrage, inflame, exasperate, antagonize, provoke, irritate greatly, rile, gall
informal make someone see red, make someone's blood boil, make someone's hackles rise, get someone's back up, hack off, drive mad/crazy, drive up the wall, get someone's dander up, get someone's goat, get up someone's nose, rattle someone's cage
British informal wind up, get on someone's wick, nark
North American informal burn up, tick off, gravel
vulgar slang piss off
British vulgar slang get on someone's tits
rare empurple
enraged, very angry, irate, furious, infuriated, angered, in a temper, raging, incandescent, fuming, seething, beside oneself, outraged, in high dudgeon
informal mad, hopping mad, wild, livid, as cross as two sticks, boiling, apoplectic, aerated, hot under the collar, on the warpath, up in arms, with all guns blazing, foaming at the mouth, steamed up, in a lather, in a paddy, in a filthy temper, fit to be tied
British informal shirty, stroppy
North American informal sore, bent out of shape, soreheaded, ticked off
Australian/New Zealand informal ropeable, snaky, crook
West Indian informal vex
British informal, dated in a bate, waxy
vulgar slang pissed off
North American vulgar slang pissed
literary wrathful, ireful, wroth