totipotent
/təʊˈtɪpət(ə)nt
/adjective Biology
(Of an immature or stem cell) capable of giving rise to any cell type or (of a blastomere) a complete embryo: totipotent embryo cells can differentiate into a hundred different cell types specialized to form such tissues as skin, marrow, and muscle...
- For the first few divisions, up to at least the 8-cell stage, all the cells of the tiny embryo are totipotent stem cells.
- Here, human or mouse embryonic stem cells, in vitro representatives of the totipotent inner cell mass blastomeres, are placed into culture.
- What he showed next were a series of experiments in which they pushed cultured, totipotent mouse embryonic stem cells to desired neural fates using the various factors he had identified as significant in vivo.
Derivatives
totipotency
- Likewise, somatic cell totipotency is demonstrated by the ability of plant cells to develop into a complete and fertile plant by in vitro somatic embryogenesis and/or organogenesis.
- He said that the demonstration of genetic totipotency of cells after prolonged culture is pivotal to combining site specific genetic manipulations and cloning.
- Somatic embryogenesis is an example of totipotency and is used as a model system for studying embryogenesis.
Origin
Early 20th century: from Latin totus 'whole' + potent1.
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