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单词 X chromosome inactivation
释义

X chromosome inactivation

noun [mass noun]
The phenomenon in a female mammal whereby the genes in one of the pair of X chromosomes are silenced, with the result that their effects are equivalent to those in the male, with only a single X chromosome.Epigenetic regulation in aging mammals can be quantitatively measured using genes subject to X chromosome inactivation and genomic imprinting....
  • While X chromosome inactivation specifically affects genes on the X chromosome, genomic imprinting modifies the activity of a subset of autosomal genes in a parent-of-origin-specific manner.
  • In mammals, methylation is required for essential developmental programs including X chromosome inactivation in females and genomic imprinting.
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更新时间:2025/3/24 6:29:39