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单词 mismatch repair
释义

mismatch repair

noun [mass noun]
A DNA repair system whereby one member of a mismatched pair of bases is converted to the normally matched base.A nearest-neighbor bias around the mutated base pair suggests that mismatch repair counteracts alkylation damage....
  • This trend may be explained by variation in mutational tendencies or by biased mismatch repair after gene conversion events.
  • These effects were examined in an otherwise wild-type background and in combination with defects in DNA mismatch repair or specialized DNA polymerases.
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更新时间:2024/11/11 0:52:57