单词	demyelinate
释义	demyelinate /diːˈmʌɪəlɪneɪt / verb [with object] (usually as adjective demyelinating) Medicine Cause the loss or destruction of myelin in (nerve tissue): a chronic demyelinating disease... Multiple sclerosis is an inflammatory, autoimmune, demyelinating disease of the central nervous system. About 50% of patients with a first demyelinating episode develop multiple sclerosis; interferon decreases this risk. Currently, demyelinating diseases are permanent, and problems worsen as time goes on because there is no way to fix the underlying problem - restoring the myelin around the axons of brain cells. Derivatives demyelination /diːmʌɪəlɪˈneɪʃ(ə)n/ noun ... Recent work is again focused on the vascular changes as a basis of the breakdown of the blood-brain barrier that precedes the inflammation and demyelination in a multiple sclerosis plaque. Postural hypotension has been associated with cerebral hypoperfusion and decreased oxygenation of the frontal lobes and with the presence of white matter lesions corresponding to demyelination and arteriosclerosis. The lesions of demyelination are histopathologically characteristic of the disease.
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