proguanil
/prəʊˈɡwɑːnɪl
/noun [mass noun] Medicine
A bitter-tasting synthetic compound derived from biguanide, used in the prevention and treatment of malaria.Mefloquine is not standard treatment internationally, although alternative drugs such as atovaquone with proguanil or artemether with lumefantrine may help to manage uncomplicated malaria in an ambulatory setting....
- They had taken chloroquine weekly and proguanil daily for chemoprophylaxis against malaria.
- Another study comparing four prophylactic regimens in civilian travelers found that overall tolerability was the same among mefloquine, doxycycline, chloroquine plus proguanil, and atovaquone plus proguanil.
Origin
1940s: from pro(pyl) + (bi)guan(ide) (a crystalline base) + -il.
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