cytochalasin
/ˌsʌɪtəʊkəˈleɪsɪn
/noun [mass noun] Biochemistry
Any of a group of polycyclic compounds produced by fungi, used experimentally in research for their property of interfering with cell processes.We measured the effect of cytochalasin D mobilization of integrins on adhesion of a leukocyte cell line to both cultured endothelium and purified ligand substrates....
- In experiments that test the effect of actin, cells were incubated for 30 min before experiments in medium containing 20 M cytochalasin D to disrupt actin filaments.
- At low concentrations, cytochalasin D is reported to inhibit actin polymerization.
Origin
1960s: from cyto- 'cell' + Greek khalasis 'dislocation'.
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