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单词 tacrine
释义

tacrine

/ˈtakriːn /
noun [mass noun] Medicine
A synthetic drug used in Alzheimer’s disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
  • An acridine derivative; chemical formula: C13H15N2Cl.
The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring....
  • These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease.
  • The pharmacologic characteristics and side effects of tacrine make it a second-line agent.

Origin

1960s: from t(etra-) + acr(id)ine.

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更新时间:2024/11/10 19:07:07