Definition of von Willebrand's disease in English:
von Willebrand's disease
nounˈwɪləbrandvän ˈviləbränts dəˌzēz
mass nounMedicine An inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).
Example sentencesExamples
- The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.
- Bloat, epilepsy and heart related problems are also reported, as are von Willebrand's disease and hemophilia A.
- There is also impairment of the platelet response to thrombin, collagen, fibrinogen, and von Willebrand factor.
- Patients with Type 3 (and some with Type 2A and 2B) will need treatment with humate p, a medication derived from human plasma that contains both factor VIII and von Willebrand factor.
- In most patients with von Willebrand disease, factor VIII activity and plasma levels of von Willebrand factor are decreased.
Origin
1940s: named after Erik A. von Willebrand (1870–1949), Finnish physician.
Definition of von Willebrand's disease in US English:
von Willebrand's disease
nounvän ˈviləbränts dəˌzēz
Medicine An inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).
Example sentencesExamples
- Patients with Type 3 (and some with Type 2A and 2B) will need treatment with humate p, a medication derived from human plasma that contains both factor VIII and von Willebrand factor.
- The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.
- In most patients with von Willebrand disease, factor VIII activity and plasma levels of von Willebrand factor are decreased.
- Bloat, epilepsy and heart related problems are also reported, as are von Willebrand's disease and hemophilia A.
- There is also impairment of the platelet response to thrombin, collagen, fibrinogen, and von Willebrand factor.
Origin
1940s: named after Erik A. von Willebrand (1870–1949), Finnish physician.