| 释义 |
Definition of voltage clamp in English: voltage clampnoun Physiology A constant electrical potential applied to a cell membrane, typically in order to measure ionic currents. Example sentencesExamples - After the proper internal and external solutions were introduced, the voltage clamp was turned on at about the 20th - 23rd minute, and the fiber was repolarized.
- The two-electrode voltage clamp of a single cell can be used to assay transport, but this can only be applied to certain cell types of intact plants.
- The lack of expression for a mutant was defined as no currents in a two-electrode voltage clamp from at least three different RNA injections and at least two different clones.
- The easiest method of measuring charge transfer across the membrane is the whole-cell voltage clamp because all motor charges in the cell contribute to the signal, making the signal large.
- Under voltage clamp, we measured the membrane current of isolated photoreceptors with tight-seal electrodes in the whole-cell mode.
- In most experiments, we partially compensated the membrane transients to speed the membrane voltage clamp.
verb [with object]Physiology Apply a voltage clamp to (a membrane, cell, etc.) oocytes were voltage-clamped at −80 to −100 mV Example sentencesExamples - We cannot experimentally distinguish between this model and the one shown in Fig.8 because this would require performing tracer-flux experiments from a single voltage-clamped cell.
- The membrane potential was voltage-clamped to 0 mV and cells were allowed to equilibrate for 5-10 min before commencement of the experiment.
- The cells were voltage-clamped and perfused with an artificial intracellular solution containing 15 mM EGTA to ensure that the bulk of the Ca 2 + mobilized by depolarization is bound to this extrinsic buffer.
- Second, we have designed the circuit to remove series resistance error in voltage-clamping the cell.
Definition of voltage clamp in US English: voltage clampnoun Physiology A constant electrical potential applied to a cell membrane, typically in order to measure ionic currents. Example sentencesExamples - Under voltage clamp, we measured the membrane current of isolated photoreceptors with tight-seal electrodes in the whole-cell mode.
- In most experiments, we partially compensated the membrane transients to speed the membrane voltage clamp.
- After the proper internal and external solutions were introduced, the voltage clamp was turned on at about the 20th - 23rd minute, and the fiber was repolarized.
- The lack of expression for a mutant was defined as no currents in a two-electrode voltage clamp from at least three different RNA injections and at least two different clones.
- The easiest method of measuring charge transfer across the membrane is the whole-cell voltage clamp because all motor charges in the cell contribute to the signal, making the signal large.
- The two-electrode voltage clamp of a single cell can be used to assay transport, but this can only be applied to certain cell types of intact plants.
verb [with object]Physiology Apply a voltage clamp to (a membrane, cell, etc.) oocytes were voltage-clamped at −80 to −100 mV Example sentencesExamples - Second, we have designed the circuit to remove series resistance error in voltage-clamping the cell.
- The membrane potential was voltage-clamped to 0 mV and cells were allowed to equilibrate for 5-10 min before commencement of the experiment.
- The cells were voltage-clamped and perfused with an artificial intracellular solution containing 15 mM EGTA to ensure that the bulk of the Ca 2 + mobilized by depolarization is bound to this extrinsic buffer.
- We cannot experimentally distinguish between this model and the one shown in Fig.8 because this would require performing tracer-flux experiments from a single voltage-clamped cell.
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