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单词 tamoxifen
释义

Definition of tamoxifen in English:

tamoxifen

noun təˈmɒksɪfɛntəˈmäksəfən
mass nounMedicine
  • A synthetic drug used to treat breast cancer and infertility in women. It acts as an oestrogen antagonist.

    Example sentencesExamples
    • These treatments may involve drugs such as tamoxifen, which are meant to prevent the cancer from growing again.
    • We do not know if raloxifene is better than tamoxifen.
    • As with all medicines, tamoxifen has side effects that may affect some women and not others.
    • Patients managed as outpatients (such as those treated with tamoxifen only) were likely to be missed.
    • Current treatment commonly centres on tamoxifen, another drug which shrinks tumours.
    • As this history is often incomplete, our measured population of all patients on tamoxifen is grossly underestimated.
    • What are the findings from the third study, which examines switching to an aromatase inhibitor after two to three years of tamoxifen?
    • The effect found for tamoxifen also reduced the overall incidence of osteoporotic fractures of the hip, spine and radius by 19%.
    • As a preventive measure, taking tamoxifen doesn't guarantee that you'll remain cancer-free.
    • The question of how long patients should continue taking the drug is important because tamoxifen is not problem free.
    • The authors suggest that tamoxifen may be underused in selected groups of women who could benefit from prophylaxis.
    • About half in each of these groups were treated with chemotherapy followed by five years of tamoxifen.
    • However, personal history, such as abnormal biopsy, was highly correlated with the decision to take tamoxifen.
    • This patient's doctor may be able to get her free tamoxifen.
    • The risk did not decrease after discontinuation of tamoxifen and was not modified by other risk factors for endometrial cancer.
    • ‘But greater use of tamoxifen has had a huge impact over the past 10 years,’ he added.
    • In addition to the initial therapy, most patients received tamoxifen in a dosage of 20 mg daily as adjuvant treatment.
    • The risk is small compared to the benefits of using tamoxifen to treat breast cancer.
    • This crystalline retinopathy is rarely seen with standard doses of tamoxifen, but when present it can cause a substantial progressive drop in visual acuity.
    • Cataract surgery was required approximately twice as often among women who took tamoxifen.

Origin

1970s: an arbitrary formation based on trans-, amine, oxy-2, phenol, elements of the drug's chemical name.

 
 

Definition of tamoxifen in US English:

tamoxifen

nountəˈmäksəfən
Medicine
  • A synthetic drug used to treat breast cancer and infertility in women. It acts as an estrogen antagonist.

    Example sentencesExamples
    • Patients managed as outpatients (such as those treated with tamoxifen only) were likely to be missed.
    • The risk is small compared to the benefits of using tamoxifen to treat breast cancer.
    • These treatments may involve drugs such as tamoxifen, which are meant to prevent the cancer from growing again.
    • About half in each of these groups were treated with chemotherapy followed by five years of tamoxifen.
    • As a preventive measure, taking tamoxifen doesn't guarantee that you'll remain cancer-free.
    • ‘But greater use of tamoxifen has had a huge impact over the past 10 years,’ he added.
    • In addition to the initial therapy, most patients received tamoxifen in a dosage of 20 mg daily as adjuvant treatment.
    • The question of how long patients should continue taking the drug is important because tamoxifen is not problem free.
    • We do not know if raloxifene is better than tamoxifen.
    • The effect found for tamoxifen also reduced the overall incidence of osteoporotic fractures of the hip, spine and radius by 19%.
    • This crystalline retinopathy is rarely seen with standard doses of tamoxifen, but when present it can cause a substantial progressive drop in visual acuity.
    • However, personal history, such as abnormal biopsy, was highly correlated with the decision to take tamoxifen.
    • Cataract surgery was required approximately twice as often among women who took tamoxifen.
    • The risk did not decrease after discontinuation of tamoxifen and was not modified by other risk factors for endometrial cancer.
    • As with all medicines, tamoxifen has side effects that may affect some women and not others.
    • This patient's doctor may be able to get her free tamoxifen.
    • What are the findings from the third study, which examines switching to an aromatase inhibitor after two to three years of tamoxifen?
    • Current treatment commonly centres on tamoxifen, another drug which shrinks tumours.
    • As this history is often incomplete, our measured population of all patients on tamoxifen is grossly underestimated.
    • The authors suggest that tamoxifen may be underused in selected groups of women who could benefit from prophylaxis.

Origin

1970s: an arbitrary formation based on trans-, amine, oxy-, phenol, elements of the drug's chemical name.

 
 
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更新时间:2024/11/10 22:08:01