Definition of tacrine in English:

tacrine

nounˈtakriːnˈtakrēn

mass nounMedicine

A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
An acridine derivative; chemical formula: C₁₃H₁₅N₂Cl
Example sentencesExamples
- There have been no direct comparison studies to tacrine or donepezil.
- Monitoring of serum transaminase levels is recommended with use of tacrine because of potential hepatotoxicity.
- The pharmacologic characteristics and side effects of tacrine make it a second-line agent.
- These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease.
- The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring.

Origin

1960s: from t(etra-) + acr(id)ine.

Definition of tacrine in US English:

tacrine

nounˈtakrēn

Medicine

A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function.
An acridine derivative; chemical formula: C₁₃H₁₅N₂Cl
Example sentencesExamples
- These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease.
- The pharmacologic characteristics and side effects of tacrine make it a second-line agent.
- The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring.
- There have been no direct comparison studies to tacrine or donepezil.
- Monitoring of serum transaminase levels is recommended with use of tacrine because of potential hepatotoxicity.

Origin

1960s: from t(etra-) + acr(id)ine.

单词	tacrine
释义	Definition of tacrine in English: tacrine nounˈtakriːnˈtakrēn mass nounMedicine A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function. An acridine derivative; chemical formula: C₁₃H₁₅N₂Cl Example sentencesExamples There have been no direct comparison studies to tacrine or donepezil. Monitoring of serum transaminase levels is recommended with use of tacrine because of potential hepatotoxicity. The pharmacologic characteristics and side effects of tacrine make it a second-line agent. These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease. The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring. Origin 1960s: from t(etra-) + acr(id)ine. Definition of tacrine in US English: tacrine nounˈtakrēn Medicine A synthetic drug used in Alzheimer's disease to inhibit the breakdown of acetylcholine by cholinesterase and thereby enhance neurological function. An acridine derivative; chemical formula: C₁₃H₁₅N₂Cl Example sentencesExamples These effects are comparable to those of the drug tacrine, which is prescribed for Alzheimer's disease. The pharmacologic characteristics and side effects of tacrine make it a second-line agent. The cholinesterase inhibitor tacrine is used rarely because of potential liver toxicity and the need for frequent laboratory monitoring. There have been no direct comparison studies to tacrine or donepezil. Monitoring of serum transaminase levels is recommended with use of tacrine because of potential hepatotoxicity. Origin 1960s: from t(etra-) + acr(id)ine.
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