Definition of tolbutamide in English:
tolbutamide
noun tɒlˈbjuːtəmʌɪdtälˈbyo͞odəˌmīd
mass nounMedicine A synthetic compound used to lower blood sugar levels in the treatment of diabetes.
Alternative name: 1-butyl-3-tosylurea; chemical formula: C₁₂H₁₈N₂O₃S
Example sentencesExamples
- Alcohol-extracted charantin from Momordica charantia consists of mixed steroids and was found to be more potent than the oral hypoglycemic agent tolbutamide in an animal study.
- Examples of sulfonylureas include tolbutamide, chlorpropamide, glyburide and glipizide.
- In some studies, karela extract has shown more hypoglycemic effects than the drug tolbutamide.
- Based on studies of the distribution of first-generation sulfonylureas into breast milk, the AAP considers tolbutamide to be compatible with breast-feeding.
- For example, sulfonamides used for infection were noted to lower blood sugar and led to drugs such as tolbutamide for diabetes.
Origin
1950s: from tol(uene) + but(yl) + amide.