Definition of transactivation in English:
transactivation
noun ˌtrɑːns--nz-ˌtransaktɪˈveɪʃ(ə)ntranˌsaktəˈvāSHən
mass nounBiochemistry Activation of a gene at one locus by the presence of a particular gene at another locus, typically following infection by a virus.
Example sentencesExamples
- Thus, transactivation may account for most of the GC side effects, such as diabetes, arterial hypertension, edema, and glaucoma.
- These injurious substances have been reported to activate EGFR through direct ligand-mediated activation, or via transactivation.
- In mouse pituitary gonadotrope cells, MMP2 and MMP9 can mediate EGFR transactivation.
- The timing of these events is complex and it should be noted that the transactivation of stress-inducible genes is not fully understood even in model systems.
- The differential transactivation potential of various HIV - 1 subtypes on these viruses needs to be explored.