释义 |
Definition of neurofibril in English: neurofibrilnoun ˌnjʊərə(ʊ)ˈfʌɪbrɪl Anatomy A fibril in the cytoplasm of a nerve cell, visible by light microscopy. Example sentencesExamples - As we age, most of us will develop alterations of neurofibrils in at least some of our neurons.
- The argyrophilic neurofibrils are unique to nerve cells.
- Bundles of these neurofibrils are called neurofilaments.
- The neurofibrils provide internal support within the neuron and there are also support cells associated with the axon.
- Silver stains show the Nissl granules occur in spaces surround by a tightly woven meshwork of neurofibrils.
Derivatives adjective Anatomy It forms the neurofibrillary tangles of Alzheimer's disease, Pick's disease, progressive supranuclear palsy, frontotemporal dementia, corticobasal degeneration, postencephalitic parkinsonism, and a handful of others. Example sentencesExamples - Molecular studies led to an understanding of the formation of extracellular plaques (flat patches) and intercellular neurofibrillary tangles, autopsy markers of Alzheimer's.
- Two microscopic changes occur in the brain in Alzheimer's disease: senile plaques develop between neurons, and neurofibrillary tangles develop within neurons.
- Among the very earliest sites of neurofibrillary pathology in Alzheimer's disease are the hippocampus and entorhinal cortex.
- Similarly, the amyloid plaques and neurofibrillary tangles that characterise Alzheimer's disease may be found at autopsy in people aged 70 years and above even if there was no clinical evidence of dementia.
Definition of neurofibril in US English: neurofibrilnoun Anatomy A fibril in the cytoplasm of a nerve cell, visible by light microscopy. Example sentencesExamples - Bundles of these neurofibrils are called neurofilaments.
- The neurofibrils provide internal support within the neuron and there are also support cells associated with the axon.
- Silver stains show the Nissl granules occur in spaces surround by a tightly woven meshwork of neurofibrils.
- The argyrophilic neurofibrils are unique to nerve cells.
- As we age, most of us will develop alterations of neurofibrils in at least some of our neurons.
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