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单词 neurodegenerative
释义

Definition of neurodegenerative in English:

neurodegenerative

adjectiveˌnjʊərə(ʊ)dɪˈdʒɛn(ə)rətɪvˌnʊroʊdəˈdʒɛnərədɪv
Medicine
  • Resulting in or characterized by degeneration of the nervous system, especially the neurons in the brain.

    an age-related neurodegenerative disorder
    Example sentencesExamples
    • The loss of ability may be associated with a number of inborn errors of metabolism or adult onset neurodegenerative disorders.
    • Using this strategy, we have identified 15 mutations affecting at least nine loci that cause gross neurodegenerative pathology.
    • Studies in Drosophila have been used to improve our understanding of human neurodegenerative diseases.
    • Postmortem and imaging studies often fail to show the characteristic abnormalities of any known neurodegenerative disorders, leading to the suspicion that a novel neuropathological process may be at large.
    • Some New Mexicans have been diagnosed with neurodegenerative afflictions which disappeared when they stopped consuming aspartame.
    • One explanation is that altered mental state is indicative of some underlying neurodegenerative process not recognized at the time of admission (i.e., Alzheimer's disease or cerebrovascular disease).
    • Dysfunction in apoptosis can lead to cancer or neurodegenerative diseases.
    • The neurodegenerative changes leading to clinical Alzheimer's disease may begin in middle age.
    • Memory loss that impairs function suggests neurodegenerative dementia, which is defined as a decline in two or more cognitive domains.
    • Baker knows firsthand the devastating effects of MSA, a neurodegenerative terminal illness that causes slurred speech and loss of muscle coordination.
    • The researchers hypothesize that the pronounced loss of these neurons could be caused either by a neurodegenerative process or an autoimmune response.
    • Glucose metabolism is a measure of brain cell activity, and reduced glucose metabolism can be a very sensitive indicator of brain damage and an early indicator of neurodegenerative disease.
    • The challenge will be in identifying the biochemical changes associated with mutations for each neurodegenerative disease.
    • He was appointed consultant paediatrician at the Queen Elizabeth Hospital for Children in 1954 and during the next 12 years published first descriptions of many metabolic and neurodegenerative diseases.
    • Furthermore, many of the proteins encoded by genes implicated in neurodegenerative diseases interact with cytoskeletal proteins.
    • Patients with concomitant disease were included if their conditions were controlled, but patients with neurodegenerative conditions and those who had already received cholinesterase inhibitor therapy were excluded.
    • These shape changes seem to be tied to onset of symptoms and may be neurodegenerative in nature.
    • Mitochondrial dysfunction is a common feature of several neurodegenerative disorders.
    • The alpha-synuclein protein, which is found broadly in the brain, has been implicated in several neurodegenerative disorders.
    • It can be used to stimulate areas of the brain that were previously inactive due to injury or neurodegenerative processes.
 
 

Definition of neurodegenerative in US English:

neurodegenerative

adjectiveˌnʊroʊdəˈdʒɛnərədɪvˌno͝orōdəˈjenərədiv
Medicine
  • Resulting in or characterized by degeneration of the nervous system, especially the neurons in the brain.

    an age-related neurodegenerative disorder
    Example sentencesExamples
    • Using this strategy, we have identified 15 mutations affecting at least nine loci that cause gross neurodegenerative pathology.
    • The researchers hypothesize that the pronounced loss of these neurons could be caused either by a neurodegenerative process or an autoimmune response.
    • He was appointed consultant paediatrician at the Queen Elizabeth Hospital for Children in 1954 and during the next 12 years published first descriptions of many metabolic and neurodegenerative diseases.
    • It can be used to stimulate areas of the brain that were previously inactive due to injury or neurodegenerative processes.
    • Baker knows firsthand the devastating effects of MSA, a neurodegenerative terminal illness that causes slurred speech and loss of muscle coordination.
    • Some New Mexicans have been diagnosed with neurodegenerative afflictions which disappeared when they stopped consuming aspartame.
    • The loss of ability may be associated with a number of inborn errors of metabolism or adult onset neurodegenerative disorders.
    • The alpha-synuclein protein, which is found broadly in the brain, has been implicated in several neurodegenerative disorders.
    • The neurodegenerative changes leading to clinical Alzheimer's disease may begin in middle age.
    • One explanation is that altered mental state is indicative of some underlying neurodegenerative process not recognized at the time of admission (i.e., Alzheimer's disease or cerebrovascular disease).
    • Furthermore, many of the proteins encoded by genes implicated in neurodegenerative diseases interact with cytoskeletal proteins.
    • Glucose metabolism is a measure of brain cell activity, and reduced glucose metabolism can be a very sensitive indicator of brain damage and an early indicator of neurodegenerative disease.
    • Mitochondrial dysfunction is a common feature of several neurodegenerative disorders.
    • Dysfunction in apoptosis can lead to cancer or neurodegenerative diseases.
    • Memory loss that impairs function suggests neurodegenerative dementia, which is defined as a decline in two or more cognitive domains.
    • The challenge will be in identifying the biochemical changes associated with mutations for each neurodegenerative disease.
    • Studies in Drosophila have been used to improve our understanding of human neurodegenerative diseases.
    • These shape changes seem to be tied to onset of symptoms and may be neurodegenerative in nature.
    • Postmortem and imaging studies often fail to show the characteristic abnormalities of any known neurodegenerative disorders, leading to the suspicion that a novel neuropathological process may be at large.
    • Patients with concomitant disease were included if their conditions were controlled, but patients with neurodegenerative conditions and those who had already received cholinesterase inhibitor therapy were excluded.
 
 
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更新时间:2024/12/23 17:47:07