Definition of neostigmine in English:
neostigmine
noun ˌniːə(ʊ)ˈstɪɡmiːnˌnēōˈstiɡmēn
mass nounMedicine A synthetic compound with the property of inhibiting cholinesterase, used to treat ileus, glaucoma, and myasthenia gravis.
Example sentencesExamples
- The study was terminated with the administration of atropine and neostigmine to reverse muscle paralysis.
- This inhibition was observed in both the directly and indirectly stimulated contractions, and was not changed by addition of neostigmine, an acetylcholine esterase inhibitor.
- The use of neostigmine to antagonise neuromuscular blockade may increase bowel motility and result in a higher rate of anastomotic leakage.
- To reverse the muscle relaxation, neostigmine and atropine were used at the end of surgery.
- At the end of procedures, the neuromuscular blockade was reversed, if necessary, with neostigmine, 0.03 mg/kg, and atropine, 0.015 mg/kg.
Origin
1940s: from neo- 'new', on the pattern of physostigmine.