1(A) Any of several poisonous plants of the family Crassulaceae, especially species of the genus Tylecodon (formerly Cotyledon). (b) The poisonous plant Lessertia annularis of the family Fabaceae (Leguminosae). rare.

2Veterinary Medicine. A disorder of goats and sheep characterized by torticollis, convulsions, colic, collapse, and often death, caused by the ingestion of any of a variety of poisonous plants, especially of the genus Tylecodon.