Definition of plasminogen in English:
plasminogen
noun plazˈmɪnədʒ(ə)nplazˈminəˌjən
mass nounBiochemistry The inactive precursor of the enzyme plasmin, present in blood.
as modifier plasminogen activator
Example sentencesExamples
- This is performed largely by the enzyme plasmin, generated from its inactive precursor, plasminogen.
- Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.
- Within the fibrinolytic system, plasmin is generated from plasminogen by tissue plasminogen activator, which upon activation lyses fibrin clots.
- The Borrelia need plasminogen from human blood to migrate to the tick's salivary glands and then infect the human.
- It produces an antifibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules.