释义 |
Definition of Barr body in English: Barr bodynoun bɑːˈbɒdiˈbär ˌbädē Physiology A small, densely staining structure in the cell nuclei of females, consisting of a condensed, inactive X chromosome. It is regarded as diagnostic of genetic femaleness. Example sentencesExamples - If the Barr bodies of a normal female were missing, she would exhibit Turners Syndrome.
- In some tissues, the inactive X chromosome can be identified in the nucleus as a Barr body and X inactivation provides an important model for the inheritance of gene expression.
- If the child is genetically female then a Barr body should be evident in approximately 10-20 percent of the cells.
- The formation of Barr bodies is the strategy that humans use for what is called dosage compensation.
- We now know that the ‘darkly staining’ Barr body is the condensed, inactive X chromosome.
Origin 1960s: named after the Canadian anatomist M. L. Barr (1908–95). Definition of Barr body in US English: Barr bodynounˈbär ˌbädē Physiology A small, densely staining structure in the cell nuclei of female mammals, consisting of a condensed, inactive X chromosome. It is regarded as diagnostic of genetic femaleness. Example sentencesExamples - The formation of Barr bodies is the strategy that humans use for what is called dosage compensation.
- In some tissues, the inactive X chromosome can be identified in the nucleus as a Barr body and X inactivation provides an important model for the inheritance of gene expression.
- If the Barr bodies of a normal female were missing, she would exhibit Turners Syndrome.
- We now know that the ‘darkly staining’ Barr body is the condensed, inactive X chromosome.
- If the child is genetically female then a Barr body should be evident in approximately 10-20 percent of the cells.
Origin 1960s: named after the Canadian anatomist M. L. Barr (1908–95). |