Definition of hypermutable in English:
hypermutable
adjective hʌɪpəˈmjʊːtəb(ə)lˌhīpərˈmyo͞odəb(ə)l
Genetics Of or in a state in which mutation is abnormally frequent.
Example sentencesExamples
- As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles.
- High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites.
- After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site.
- The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides.
- The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides.
Definition of hypermutable in US English:
hypermutable
adjectiveˌhīpərˈmyo͞odəb(ə)l
Genetics Of or in a state in which mutation is abnormally frequent.
Example sentencesExamples
- The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides.
- After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site.
- As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles.
- High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites.
- The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides.