Definition of oncogenic in English:

oncogenic

adjective ˌɒŋkə(ʊ)ˈdʒɛnɪkˌɑnkoʊˈdʒɛnɪk

Medicine

Causing development of a tumour or tumours.
Example sentencesExamples
- Efavirenz should not be used during pregnancy because of possible teratogenicity, and the potential for oncogenic toxicity is unknown.
- These early HPV tests did not achieve widespread use because they did not detect all oncogenic HPV genotypes.
- The prevalence of oncogenic HPV was too high to permit effective triage of LSIL using HPV DNA testing by Hybrid Capture 2.
- It has been hoped that the ability to identify patients with oncogenic HPV types will lead to improved detection in women more likely to have SILs.
- Although infections with oncogenic strains of human papillomavirus remain the prime cause of cervical cancer, infection with some strains of Chlamydia trachomatis seem to contribute to that risk.
- However, if liquid-based cytology is used, reflex HPV DNA testing for oncogenic HPV types is the preferred method of evaluation (AI recommendation).
- Presence of oncogenic HPV types 16 and 18 DNA was done by polymerase chain reaction.
- Although integration of oncogenic HPV is an important event in the pathogenesis of the majority of cervical and some vulvar carcinomas, HPV alone is insufficient for the evolution of these tumors.
- In the preliminary investigations using multiple PCR on endoscopie EC biopsies, a significant prevalence of the highly oncogenic HPV - 16 was documented.
- Context.-Cervicography and oncogenic human papillomavirus testing have been proposed for improving the accuracy of cervical cancer screening.
- One good quality assurance indicator for the Digene HC2 assay would be to monitor the frequency of oncogenic HPV types in atypical squamous cell specimens.
- There may be a direct correlation between the number of copies of an oncogenic HPV type within a cell or in an anatomic site and the risk of developing HPV-related disease.
- In histologic terms, it seems that a sizable percentage of CIN 3 cases arise from oncogenic HPV infections without transiting through diagnosed CIN 1 or even equivocal microscopic lesions.
- The frequency of oncogenic HPV detection and underlying lesions of CIN 2 or higher and CIN 3 or higher in women with ASCUS-H was intermediate between that of ASCUS-L and HSIL.
- It is caused by infections with oncogenic strains of the human papillomavirus.
- The diagnoses of LSIL and ASC-US with oncogenic HPV types are clinically equivalent.
- Thus, the term high-risk or oncogenic HPV is a relative misnomer.15
- It is also acceptable to perform repeat HPV DNA testing at 12 months and refer the patient for colposcopy if oncogenic HPV types persist (BII recommendation).
- A total of 98.9 percent of women with HSIL test positive for oncogenic HPV types.
- Cross-reactivity occurs between oncogenic and nononcogenic panels, resulting in false-positive results for both oncogenic and nononcogenic HPV types.

Derivatives

oncogenesis

noun ˌɒŋkə(ʊ)ˈdʒɛnəsɪsˌɑŋkoʊˈdʒɛnəsəs

mass noun

Medicine

The development of a tumour or tumours.
genes that promote oncogenesis in melanoma
Example sentencesExamples
- the molecular mechanisms of oncogenesis
- The phosphorylated one enhances oncogenesis, whereas the nonphosphorylated EZH2 works to inhibit cell growth.
- It is well known that obesity increases the risk of cardiovascular diseases, but its role in oncogenesis is less understood.
- At the site of metaplastic transformation, the HPV is incorporated into the host DNA, and oncogenesis is initiated.

oncogenicity

noun ˌɒŋkə(ʊ)dʒɛˈnɪsɪti

Medicine

Furthermore, associations between genetically characterized disorders such as NF and a spectrum of neoplasia may lend insights into the oncogenicity of specific inherited genetic mutations.
Example sentencesExamples
- The Glycoprotein D (US6) Homolog Is Not Essential for Oncogenicity or Horizontal Transmission of Marek's Disease Virus
- This is not to mention the myriad of problems with gene and protein expression, microenvironmental factors, angiogenesis, aging, and oncogenicity that need to be resolved before targeting cells and genes to the lung in humans.
- It comprised the L1 capsid protein devoid of other genes, so that in effect the study subjects were vaccinated with an ‘empty’ virus, eliminating the risk of oncogenicity from the vaccine itself.
- The negative response observed in this assay is consistent with the theory that tumours observed in mouse oncogenicity studies are non-genotoxic in origin.

Definition of oncogenic in US English:

oncogenic

adjectiveˌɑnkoʊˈdʒɛnɪkˌänkōˈjenik

Medicine

Causing development of a tumor or tumors.
Example sentencesExamples
- There may be a direct correlation between the number of copies of an oncogenic HPV type within a cell or in an anatomic site and the risk of developing HPV-related disease.
- In the preliminary investigations using multiple PCR on endoscopie EC biopsies, a significant prevalence of the highly oncogenic HPV - 16 was documented.
- These early HPV tests did not achieve widespread use because they did not detect all oncogenic HPV genotypes.
- Thus, the term high-risk or oncogenic HPV is a relative misnomer.15
- Efavirenz should not be used during pregnancy because of possible teratogenicity, and the potential for oncogenic toxicity is unknown.
- It is also acceptable to perform repeat HPV DNA testing at 12 months and refer the patient for colposcopy if oncogenic HPV types persist (BII recommendation).
- The prevalence of oncogenic HPV was too high to permit effective triage of LSIL using HPV DNA testing by Hybrid Capture 2.
- The diagnoses of LSIL and ASC-US with oncogenic HPV types are clinically equivalent.
- It is caused by infections with oncogenic strains of the human papillomavirus.
- Although integration of oncogenic HPV is an important event in the pathogenesis of the majority of cervical and some vulvar carcinomas, HPV alone is insufficient for the evolution of these tumors.
- A total of 98.9 percent of women with HSIL test positive for oncogenic HPV types.
- Presence of oncogenic HPV types 16 and 18 DNA was done by polymerase chain reaction.
- Context.-Cervicography and oncogenic human papillomavirus testing have been proposed for improving the accuracy of cervical cancer screening.
- It has been hoped that the ability to identify patients with oncogenic HPV types will lead to improved detection in women more likely to have SILs.
- The frequency of oncogenic HPV detection and underlying lesions of CIN 2 or higher and CIN 3 or higher in women with ASCUS-H was intermediate between that of ASCUS-L and HSIL.
- Cross-reactivity occurs between oncogenic and nononcogenic panels, resulting in false-positive results for both oncogenic and nononcogenic HPV types.
- Although infections with oncogenic strains of human papillomavirus remain the prime cause of cervical cancer, infection with some strains of Chlamydia trachomatis seem to contribute to that risk.
- In histologic terms, it seems that a sizable percentage of CIN 3 cases arise from oncogenic HPV infections without transiting through diagnosed CIN 1 or even equivocal microscopic lesions.
- One good quality assurance indicator for the Digene HC2 assay would be to monitor the frequency of oncogenic HPV types in atypical squamous cell specimens.
- However, if liquid-based cytology is used, reflex HPV DNA testing for oncogenic HPV types is the preferred method of evaluation (AI recommendation).

单词	oncogenic
释义	Definition of oncogenic in English: oncogenic adjective ˌɒŋkə(ʊ)ˈdʒɛnɪkˌɑnkoʊˈdʒɛnɪk Medicine Causing development of a tumour or tumours. Example sentencesExamples Efavirenz should not be used during pregnancy because of possible teratogenicity, and the potential for oncogenic toxicity is unknown. These early HPV tests did not achieve widespread use because they did not detect all oncogenic HPV genotypes. The prevalence of oncogenic HPV was too high to permit effective triage of LSIL using HPV DNA testing by Hybrid Capture 2. It has been hoped that the ability to identify patients with oncogenic HPV types will lead to improved detection in women more likely to have SILs. Although infections with oncogenic strains of human papillomavirus remain the prime cause of cervical cancer, infection with some strains of Chlamydia trachomatis seem to contribute to that risk. However, if liquid-based cytology is used, reflex HPV DNA testing for oncogenic HPV types is the preferred method of evaluation (AI recommendation). Presence of oncogenic HPV types 16 and 18 DNA was done by polymerase chain reaction. Although integration of oncogenic HPV is an important event in the pathogenesis of the majority of cervical and some vulvar carcinomas, HPV alone is insufficient for the evolution of these tumors. In the preliminary investigations using multiple PCR on endoscopie EC biopsies, a significant prevalence of the highly oncogenic HPV - 16 was documented. Context.-Cervicography and oncogenic human papillomavirus testing have been proposed for improving the accuracy of cervical cancer screening. One good quality assurance indicator for the Digene HC2 assay would be to monitor the frequency of oncogenic HPV types in atypical squamous cell specimens. There may be a direct correlation between the number of copies of an oncogenic HPV type within a cell or in an anatomic site and the risk of developing HPV-related disease. In histologic terms, it seems that a sizable percentage of CIN 3 cases arise from oncogenic HPV infections without transiting through diagnosed CIN 1 or even equivocal microscopic lesions. The frequency of oncogenic HPV detection and underlying lesions of CIN 2 or higher and CIN 3 or higher in women with ASCUS-H was intermediate between that of ASCUS-L and HSIL. It is caused by infections with oncogenic strains of the human papillomavirus. The diagnoses of LSIL and ASC-US with oncogenic HPV types are clinically equivalent. Thus, the term high-risk or oncogenic HPV is a relative misnomer.15 It is also acceptable to perform repeat HPV DNA testing at 12 months and refer the patient for colposcopy if oncogenic HPV types persist (BII recommendation). A total of 98.9 percent of women with HSIL test positive for oncogenic HPV types. Cross-reactivity occurs between oncogenic and nononcogenic panels, resulting in false-positive results for both oncogenic and nononcogenic HPV types. Derivatives oncogenesis noun ˌɒŋkə(ʊ)ˈdʒɛnəsɪsˌɑŋkoʊˈdʒɛnəsəs mass nounMedicine The development of a tumour or tumours. genes that promote oncogenesis in melanoma Example sentencesExamples the molecular mechanisms of oncogenesis The phosphorylated one enhances oncogenesis, whereas the nonphosphorylated EZH2 works to inhibit cell growth. It is well known that obesity increases the risk of cardiovascular diseases, but its role in oncogenesis is less understood. At the site of metaplastic transformation, the HPV is incorporated into the host DNA, and oncogenesis is initiated. oncogenicity noun ˌɒŋkə(ʊ)dʒɛˈnɪsɪti Medicine Furthermore, associations between genetically characterized disorders such as NF and a spectrum of neoplasia may lend insights into the oncogenicity of specific inherited genetic mutations. Example sentencesExamples The Glycoprotein D (US6) Homolog Is Not Essential for Oncogenicity or Horizontal Transmission of Marek's Disease Virus This is not to mention the myriad of problems with gene and protein expression, microenvironmental factors, angiogenesis, aging, and oncogenicity that need to be resolved before targeting cells and genes to the lung in humans. It comprised the L1 capsid protein devoid of other genes, so that in effect the study subjects were vaccinated with an ‘empty’ virus, eliminating the risk of oncogenicity from the vaccine itself. The negative response observed in this assay is consistent with the theory that tumours observed in mouse oncogenicity studies are non-genotoxic in origin. Definition of oncogenic in US English: oncogenic adjectiveˌɑnkoʊˈdʒɛnɪkˌänkōˈjenik Medicine Causing development of a tumor or tumors. Example sentencesExamples There may be a direct correlation between the number of copies of an oncogenic HPV type within a cell or in an anatomic site and the risk of developing HPV-related disease. In the preliminary investigations using multiple PCR on endoscopie EC biopsies, a significant prevalence of the highly oncogenic HPV - 16 was documented. These early HPV tests did not achieve widespread use because they did not detect all oncogenic HPV genotypes. Thus, the term high-risk or oncogenic HPV is a relative misnomer.15 Efavirenz should not be used during pregnancy because of possible teratogenicity, and the potential for oncogenic toxicity is unknown. It is also acceptable to perform repeat HPV DNA testing at 12 months and refer the patient for colposcopy if oncogenic HPV types persist (BII recommendation). The prevalence of oncogenic HPV was too high to permit effective triage of LSIL using HPV DNA testing by Hybrid Capture 2. The diagnoses of LSIL and ASC-US with oncogenic HPV types are clinically equivalent. It is caused by infections with oncogenic strains of the human papillomavirus. Although integration of oncogenic HPV is an important event in the pathogenesis of the majority of cervical and some vulvar carcinomas, HPV alone is insufficient for the evolution of these tumors. A total of 98.9 percent of women with HSIL test positive for oncogenic HPV types. Presence of oncogenic HPV types 16 and 18 DNA was done by polymerase chain reaction. Context.-Cervicography and oncogenic human papillomavirus testing have been proposed for improving the accuracy of cervical cancer screening. It has been hoped that the ability to identify patients with oncogenic HPV types will lead to improved detection in women more likely to have SILs. The frequency of oncogenic HPV detection and underlying lesions of CIN 2 or higher and CIN 3 or higher in women with ASCUS-H was intermediate between that of ASCUS-L and HSIL. Cross-reactivity occurs between oncogenic and nononcogenic panels, resulting in false-positive results for both oncogenic and nononcogenic HPV types. Although infections with oncogenic strains of human papillomavirus remain the prime cause of cervical cancer, infection with some strains of Chlamydia trachomatis seem to contribute to that risk. In histologic terms, it seems that a sizable percentage of CIN 3 cases arise from oncogenic HPV infections without transiting through diagnosed CIN 1 or even equivocal microscopic lesions. One good quality assurance indicator for the Digene HC2 assay would be to monitor the frequency of oncogenic HPV types in atypical squamous cell specimens. However, if liquid-based cytology is used, reflex HPV DNA testing for oncogenic HPV types is the preferred method of evaluation (AI recommendation).
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