Definition of pharmacophore in English:

pharmacophore

noun ˈfɑːməkəˌfɔːˈfärməkəˌfôr

A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes.
Example sentencesExamples
- The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores.
- For beta 1 selectivity, a beta-adrenergic antagonist should contain a p-substituted aryloxypropanolamine pharmacophore.
- The particular parts of a drug that cause it to bind to its receptor are together termed the pharmacophore.
- The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs.
- This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand.

Definition of pharmacophore in US English:

pharmacophore

nounˈfärməkəˌfôr

A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes.
Example sentencesExamples
- For beta 1 selectivity, a beta-adrenergic antagonist should contain a p-substituted aryloxypropanolamine pharmacophore.
- The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs.
- This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand.
- The particular parts of a drug that cause it to bind to its receptor are together termed the pharmacophore.
- The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores.

单词	pharmacophore
释义	Definition of pharmacophore in English: pharmacophore noun ˈfɑːməkəˌfɔːˈfärməkəˌfôr A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes. Example sentencesExamples The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores. For beta 1 selectivity, a beta-adrenergic antagonist should contain a p-substituted aryloxypropanolamine pharmacophore. The particular parts of a drug that cause it to bind to its receptor are together termed the pharmacophore. The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs. This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand. Definition of pharmacophore in US English: pharmacophore nounˈfärməkəˌfôr A part of a molecular structure that is responsible for a particular biological or pharmacological interaction that it undergoes. Example sentencesExamples For beta 1 selectivity, a beta-adrenergic antagonist should contain a p-substituted aryloxypropanolamine pharmacophore. The phenothiazine ring is a well-known pharmacophore, and chlorpromazine is a prototype of this class of antipsychotic drugs. This pharmacophore identifies two important hydrogen-bonding interactions at opposite ends of the ligand. The particular parts of a drug that cause it to bind to its receptor are together termed the pharmacophore. The similar mechanism of action of paclitaxel, the epothilones, discodermolide and eleutherobin has led to the suggestion that these structurally dissimilar substances possess common pharmacophores.
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