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单词 purine
释义

Definition of purine in English:

purine

noun ˈpjʊəriːnˈpjʊrin
mass nounChemistry
  • 1A colourless crystalline compound with basic properties, forming uric acid on oxidation.

    A bicyclic compound; chemical formula: C₅H₄N₄

    Example sentencesExamples
    • The major enzymological studies underway in the field of biochemistry prior to 1950 unfortunately were focused on carbon metabolism, not on amino acid, vitamin, purine, or pyrimidine biosynthesis.
    • All these foods contain high levels of purine, which the body metabolises into uric acid - hence gout.
    • Uric acid is a byproduct of the metabolism of purine, a protein found particularly in red meat and offal, game, seafood and alcoholic drinks (particularly beer, lager, port and red wine).
    • Conversely, the reaction of purine and pyrimidine nucleobases with alkylating and oxidizing agents generally results in site-specific cleavage.
    • Scientists have long known that gout develops when joints become fouled with crystals of uric acid, which is a natural digestion product of purine.
    1. 1.1count noun A substituted derivative of purine, especially the bases adenine and guanine present in DNA.
      Example sentencesExamples
      • This view was reinforced by the elucidation of Z DNA and Z RNA structures, where the syn purines are mostly guanines.
      • Indeed, all the genes encoding enzymes required for de novo AMP biosynthesis are repressed at the transcriptional level by the presence of extracellular purines (adenine or hypoxanthine).
      • Two other ways of recoding the data were cited: eliminating third codon positions and recoding nucleotides as purines and pyrimidines.
      • In comparison with the deamination of cytosine to uracil, the deamination of DNA purines is a minor reaction.
      • The purines adenine and guanine are constituents of DNA.

Origin

Late 19th century: from German Purin, from Latin purus 'pure' + uricum 'uric acid' + -ine4.

 
 

Definition of purine in US English:

purine

nounˈpyo͝orēnˈpjʊrin
Chemistry
  • 1A colorless crystalline compound with basic properties, forming uric acid on oxidation.

    A bicyclic compound; chemical formula: C₅H₄N₄

    Example sentencesExamples
    • All these foods contain high levels of purine, which the body metabolises into uric acid - hence gout.
    • Conversely, the reaction of purine and pyrimidine nucleobases with alkylating and oxidizing agents generally results in site-specific cleavage.
    • Scientists have long known that gout develops when joints become fouled with crystals of uric acid, which is a natural digestion product of purine.
    • The major enzymological studies underway in the field of biochemistry prior to 1950 unfortunately were focused on carbon metabolism, not on amino acid, vitamin, purine, or pyrimidine biosynthesis.
    • Uric acid is a byproduct of the metabolism of purine, a protein found particularly in red meat and offal, game, seafood and alcoholic drinks (particularly beer, lager, port and red wine).
    1. 1.1 A substituted derivative of purine, especially the bases adenine and guanine present in DNA.
      Example sentencesExamples
      • Indeed, all the genes encoding enzymes required for de novo AMP biosynthesis are repressed at the transcriptional level by the presence of extracellular purines (adenine or hypoxanthine).
      • The purines adenine and guanine are constituents of DNA.
      • In comparison with the deamination of cytosine to uracil, the deamination of DNA purines is a minor reaction.
      • Two other ways of recoding the data were cited: eliminating third codon positions and recoding nucleotides as purines and pyrimidines.
      • This view was reinforced by the elucidation of Z DNA and Z RNA structures, where the syn purines are mostly guanines.

Origin

Late 19th century: from German Purin, from Latin purus ‘pure’ + uricum ‘uric acid’ + -ine.

 
 
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更新时间:2024/9/22 12:33:34