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单词 nucleosome
释义

Definition of nucleosome in English:

nucleosome

noun ˈnjuːklɪə(ʊ)səʊmˈn(y)o͞oklēəˌsōm
Biology
  • A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones.

    Example sentencesExamples
    • The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation.
    • Histones form the core of the nucleosome around which DNA is wrapped.
    • DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures.
    • Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.
    • On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones.

Derivatives

  • nucleosomal

  • adjective
    Biology
    • Chromatin is a complex molecular structure composed of nucleosomal repeats in which 147 bp of DNA are wrapped around two copies of the four core histones, H2A, H2B, H3, and H4.
      Example sentencesExamples
      • Many of these changes are larger in scale than suggested from previous studies and involve a number of DNA-mediated events, including a preference for the removal of a complete turn of nucleosomal DNA.
      • The failure to recover mutations in genes encoding nucleosomal histones in this screen may be due to the presence of numerous copies of the histone gene cluster in flies.
      • Histones are small basic proteins encoded by a multigene family and are responsible for the nucleosomal organization of chromatin in eukaryotes.
      • In wild-type cells, the repressed state spreads unidirectionally through nucleosomal chromatin.
 
 

Definition of nucleosome in US English:

nucleosome

nounˈn(y)o͞oklēəˌsōm
Biology
  • A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones.

    Example sentencesExamples
    • The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation.
    • DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures.
    • Histones form the core of the nucleosome around which DNA is wrapped.
    • On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones.
    • Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.
 
 
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更新时间:2024/12/23 9:38:01