Definition of pepsinogen in English:
pepsinogen
noun pɛpˈsɪnədʒ(ə)npepˈsinəjen
mass nounBiochemistry A substance which is secreted by the stomach wall and converted into the enzyme pepsin by gastric acid.
count noun high concentrations of pepsinogens
Example sentencesExamples
- In the stomach, pepsinogen is secreted, and activated into pepsin by the acid that is secreted at the same site.
- The sensitivity of the assay is not great enough to detect the small quantity of pepsinogen known to be present in blood (presumably after direct absorption from gastric mucosal cells).
- Ginger is an excellent natural antacid because it prevents the breakdown of pepsinogen to pepsin: the latter irritates tissue to cause peptic ulcers.
- Examples of important proenzymes include pepsinogen, trypsinogen and chymotrypsinogen, which give rise to the proteolytic digestive enzymes.
- This process is autocatalytic for some pro-enzymes such as pepsinogen [23-25] and cathepsins D and E.