A severe form of anaemia caused in a fetus or newborn infant by incompatibility with the mother's blood type, typically when the mother is rhesus negative and produces antibodies which attack rhesus positive fetal blood through the placenta.
Also called erythroblastosis
Example sentencesExamples
- While an assistant pathologist at the Hospital, she published papers on haemolytic disease of the newborn.
- In addition hemolytic disease of the newborn may be due to antibodies in other blood group system antigens.
- Fetomaternal hemorrhage leads to alloimmunization of Rh D-negative mothers, resulting in an increased risk of hemolytic disease of the newborn.
- Both anti-C and anti-G are clinically significant antibodies capable of causing extravascular transfusion reactions and hemolytic disease of the newborn.
- In England and Wales, about 500 fetuses develop haemolytic disease each year, and about 25-30 babies die from haemolytic disease of the newborn.