Definition of gene amplification in US English:
gene amplification
nounˈjēn ˌampləfiˌkāSH(ə)nˈjēn ˌampləfiˌkāSH(ə)n
The multiple replication of a section of the genome, which occurs during a single cell cycle and results in the production of many copies of a specific sequence of the DNA molecule.
Example sentencesExamples
- Although the explanation for most of our metastases showing protein overexpression without gene amplification is unknown at this point, we noted a plausible explanation for the discordance in 2 of these patients.
- Over-expression of this gene is a result of gene amplification or translocation and has been detected in many human cancers.
- The protein coded by these genes is accumulated to high levels by feeding larvae and gene amplification has not resulted in different discernible functions.
- The unexpectedly common association of palindromic DNA with gene amplification has stimulated interest in understanding how large DNA palindromes form.
- Importantly, the technology eliminates the need for costly, time and labor intensive gene amplification or enzymatic interventions - two widespread methods currently used to perform such analyses.
Definition of gene amplification in US English:
gene amplification
nounˈjēn ˌampləfiˌkāSH(ə)n
The multiple replication of a section of the genome, which occurs during a single cell cycle and results in the production of many copies of a specific sequence of the DNA molecule.
Example sentencesExamples
- The unexpectedly common association of palindromic DNA with gene amplification has stimulated interest in understanding how large DNA palindromes form.
- The protein coded by these genes is accumulated to high levels by feeding larvae and gene amplification has not resulted in different discernible functions.
- Importantly, the technology eliminates the need for costly, time and labor intensive gene amplification or enzymatic interventions - two widespread methods currently used to perform such analyses.
- Although the explanation for most of our metastases showing protein overexpression without gene amplification is unknown at this point, we noted a plausible explanation for the discordance in 2 of these patients.
- Over-expression of this gene is a result of gene amplification or translocation and has been detected in many human cancers.