| 释义 |
Definition of episome in English: episomenoun ˈɛpɪsəʊmˈepəˌsōm Microbiology A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated. Compare with plasmid Example sentencesExamples - This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128.
- Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells.
- The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome.
- Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability.
- During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted.
Origin 1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some. Definition of episome in US English: episomenounˈepəˌsōm Microbiology A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated. Compare with plasmid Example sentencesExamples - The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome.
- During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted.
- Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability.
- This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128.
- Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells.
Origin 1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some. |