Definition of endonuclease in English:
endonuclease
nounˌɛndəʊˈnjʊːklɪeɪz-ˌāz
Biochemistry An enzyme which cleaves a polynucleotide chain by separating nucleotides other than the two end ones.
Example sentencesExamples
- Let us remember that they are concerned with a DNA endonuclease, so I had some experience dealing with an enzyme that cut nucleic acids.
- These blocked forks could potentially be processed into DNA breaks by an endonuclease.
- Primers and endonucleases are used in the cloning of the various constructs.
- The second involves the joining of DNA ends through the pairing of short complementary sequences, as happens with complementary overhanging DNA ends produced by endonucleases.
- Total DNA was prepared from leaves of barley after 7 days of germination and restricted with appropriate endonucleases.