释义 |
Definition of acetylate in English: acetylateverb əˈsɛtɪleɪtəˈsedlˌāt [with object]often as adjective acetylatedChemistry Introduce an acetyl group into (a molecule or compound) the acetylated forms of chloramphenicol Example sentencesExamples - Serotonin in this gland is acetylated, then methylated, forming melatonin.
- Histones (DNA packaging proteins) have lysine tails, which can be acetylated in a post-translational modification step.
- In addition to histones, some HATs can acetylate non-histone proteins, suggesting multiple roles for these enzymes.
- The proteins became acetylated instead, preventing glucose from attaching.
- The N-terminal group was acetylated to reproduce the experimental conditions at which the protein was studied.
Derivatives noun Chemistry Slowly, as researchers learned more about the structure of histones, it became evident that patterns of acetylation and methylation could be quite precise. Example sentencesExamples - From a dynamic point of view, histone-tail modifications, such as acetylation, phosphorylation, or methylation, are necessary to allow the activity of the chromatin remodeling complex.
- The acetylation of salicylic acid increased the potency of morphine by making the compound more soluble in brain fat and facilitating transfer across the blood brain barrier.
- This effect is consistent with the expected large reduction in electron density on the amino nitrogen upon acetylation thus making coordination with copper much less strong.
- Important mechanisms for epigenetic alteration of gene expression include DNA methylation and histone acetylation.
Definition of acetylate in US English: acetylateverbəˈsedlˌāt [with object]Chemistry Introduce an acetyl group into (a molecule or compound) the acetylated forms of chloramphenicol Example sentencesExamples - In addition to histones, some HATs can acetylate non-histone proteins, suggesting multiple roles for these enzymes.
- The proteins became acetylated instead, preventing glucose from attaching.
- Histones (DNA packaging proteins) have lysine tails, which can be acetylated in a post-translational modification step.
- The N-terminal group was acetylated to reproduce the experimental conditions at which the protein was studied.
- Serotonin in this gland is acetylated, then methylated, forming melatonin.
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