Definition of demyelinate in English:
demyelinate
verbdiːˈmʌɪəlɪneɪtdēˈmīələˌnāt
[with object]usually as adjective demyelinatingMedicine Cause the loss or destruction of myelin in (nerve tissue)
a chronic demyelinating disease
Example sentencesExamples
- About 50% of patients with a first demyelinating episode develop multiple sclerosis; interferon decreases this risk.
- A demyelinating disease is any condition that results in damage to the protective covering (myelin sheath) that surrounds nerves in your brain and spinal cord.
- It has already been clearly established that vaccines can lead to demyelinating disorders.
- Multiple sclerosis is an inflammatory, autoimmune, demyelinating disease of the central nervous system.
- Currently, demyelinating diseases are permanent, and problems worsen as time goes on because there is no way to fix the underlying problem - restoring the myelin around the axons of brain cells.
Derivatives
noun diːmʌɪəlɪˈneɪʃ(ə)n
Medicine The lesions of demyelination are histopathologically characteristic of the disease.
Example sentencesExamples
- Multiple sclerosis typically begin in early adulthood and is characterized by multiple areas of demyelination and sclerosis of the brain, spinal cord, or both.
- Postural hypotension has been associated with cerebral hypoperfusion and decreased oxygenation of the frontal lobes and with the presence of white matter lesions corresponding to demyelination and arteriosclerosis.
- Recent work is again focused on the vascular changes as a basis of the breakdown of the blood-brain barrier that precedes the inflammation and demyelination in a multiple sclerosis plaque.
- It might, for example, be a factor in killing oligodendrocytes, and hence triggering demyelination in Multiple Sclerosis, an autoimmune disorder.