| 释义 |
hemolytic transfusion reaction
hemolytic transfusion reaction Transfusion medicine A therapy-related event mediated by 2 different mechanisms: 1. Intravascular hemolysis mediated by complement-fixing antibodies,.2. Extravascular hemolysis mediated by noncomplement-fixing antibodies Clinical Fever, chills, pain at infusion site, intense back pain, hypotension, sense of impending doom, chest tightness, acute dyspnea, brochospasm, anaphylaxis, hyperbilirubinemia, hemoglobinuria, DIC with fibrinolysis Management Stop transfusion, treat shock–vasopressors, IV fluids, cortiocosteroids, maintain high fluid throughput, monitor anemia, transfuse with compatible blood.hemolytic transfusion reactionThe destruction of donated and infused red blood cells by antibodies in the person receiving the transfusion. See: transfusion reactionAcronymsSeeHTR |