| 释义 |
gene pool
gene pooln. The collective genetic information contained within a population of sexually reproducing organisms.gene pool n (Genetics) the sum of all the genes in an interbreeding population gene′ pool`
n. the total genetic information in the gametes of all the individuals in a population. [1945–50] gene pool
gene pool, the total of all genesgene,
the structural unit of inheritance in living organisms. A gene is, in essence, a segment of DNA that has a particular purpose, i.e., that codes for (contains the chemical information necessary for the creation of) a specific enzyme or other protein.
..... Click the link for more information. in a population of a particular species. See geneticsgenetics,
scientific study of the mechanism of heredity. While Gregor Mendel first presented his findings on the statistical laws governing the transmission of certain traits from generation to generation in 1856, it was not until the discovery and detailed study of the
..... Click the link for more information. .Gene Pool (Russian genofond), the qualitative composition and the relative quantity of the different forms (alleles) of the various genes in the population of one or another species of organism. By the term “gene pool” (the term in Russian was introduced by the Russian scientist A. S. Serebrovskii in 1928) is meant the allelic composition of the population or of all the members of the species, including all the variable characters and traits of the species or one or another selection from them, which is of interest to the researcher. When there is a sharp reduction in the number of individuals or a change in external conditions, the recessive gene pool— which is the sum total of recessive alleles that are for the most part excluded from natural selection—ensures that there will be a rapid change in the genetic makeup of the population. In the genetically less studied species, it is possible to determine the so-called phenotypic pool (a phene is an elementary character). Taking stock of hereditarily variable characters of farm animal and plant species under study, together with a determination of the frequencies of various alleles, is of great practical significance. The study of the gene pool of man has fundamental significance for human genetics. REFERENCESerebrovskii, A. S. “Genogeografiia i genofond sel’skokhoziaistvennykh zhivotnykh SSSR.” Nauchnoe slovo, 1928, no. 9.N. V. TIMOFEEV-RESOVSKII gene pool[′jēn ‚pül] (genetics) The totality of the genes of a specific population at a given time. gene pool
gene [jēn] one of the biologic units of heredity, self-reproducing, and located at a definite position (locus) on a particular chromosome. Genes make up segments of the complex deoxyribonucleic acid (DNA) molecule that controls cellular reproduction and function. There are thousands of genes in the chromosomes of each cell nucleus; they play an important role in heredity because they control the individual physical, biochemical, and physiologic traits inherited by offspring from their parents. Through the genetic code of DNA they also control the day-to-day functions and reproduction of all cells in the body. For example, the genes control the synthesis of structural proteins and also the enzymes that regulate various chemical reactions that take place in a cell.
The gene is capable of replication. When a cell multiplies by mitosis each daughter cell carries a set of genes that is an exact replica of that of the parent cell. This characteristic of replication explains how genes can carry hereditary traits through successive generations without change.allelic gene allele.complementary g's two independent pairs of nonallelic genes, neither of which will produce its effect in the absence of the other.DCC gene (deleted in colorectal carcinoma) a gene normally expressed in the mucosa of the colon but reduced or absent in a small proportion of patients with colorectal cancer.dominant gene one that produces an effect (the phenotype) in the organism regardless of the state of the corresponding allele. An example of a trait determined by a dominant gene is brown eye color. See also heredity" >heredity.histocompatibility gene one that determines the specificity of tissue antigenicity (hla antigens) and thus the compatibility of donor and recipient in tissue transplantation and blood transfusion.holandric g's genes located on the Y chromosome and appearing only in male offspring.immune response (Ir) g's genes of the complex" >major histocompatibility complex that govern the immune response to individual immunogens.immune suppressor (Is) g's genes that govern the formation of suppressor lymphocytes" >T lymphocytes.immunoglobulin g's the genes coding for immunoglobulin heavy and light chains, which are organized in three loci coding for κ light chains, λ light chains, and heavy chains.K-ras gene a type of oncogene.lethal gene one whose presence brings about the death of the organism or permits survival only under certain conditions.major gene a gene whose effect on the phenotype is always evident, regardless of how this effect is modified by other genes.mutant gene one that has undergone a detectable mutation.operator gene one serving as a starting point for reading the genetic code, and which, through interaction with a repressor, controls the activity of structural genes associated with it in the operon.gene pool all of the genes possessed by all of the members of a population that will reproduce.recessive gene one that produces an effect in the organism only when it is transmitted by both parents, i.e., only when the individual is homozygous. See also heredity.regulator gene (repressor gene) one that synthesizes repressor, a substance which, through interaction with the operator gene, switches off the activity of the structural genes associated with it in the operon.sex-linked gene a gene carried on a sex chromosome (X or Y); only X linkage has clinical significance. See gene" >X-linked gene.gene splicing recombinant dna technology.structural gene one that forms templates for messenger RNA and is thereby responsible for the amino acid sequence of specific polypeptides.tumor suppressor gene a gene whose function is to limit cell proliferation and loss of whose function leads to cell transformation and tumor growth; called also antioncogene.X-linked gene a gene carried on the X chromosome; the corresponding trait, whether dominant or recessive, is always expressed in males, who have only one X chromosome. the term “X-linked” is sometimes used synonymously with “sex-linked,” since no genetic disorders have as yet been associated with genes on the Y chromosome.gene poolthe set of the genes available for inheritance in a particular mating population.gene pooln. The collective genetic information contained within a population of sexually reproducing organisms.gene pool the sum total of all the genes of all BREEDING INDIVIDUALS in a population at a particular time, represented by their GAMETES. Note that those individuals which are too young to breed (juveniles) or those that have undergone GENETIC DEATH do not contribute to the gene pool.LegalSeePoolFinancialSeepoolThesaurusSeegene |