GNPTG

A gene on chromosome 16p13.3 that encodes the gamma subunit of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of 2 alpha, 2 beta and 2 gamma subunits. In the Golgi apparatus, GNPTG catalyses the first step in the synthesis of mannose 6-phosphate recognition markers on oligosaccharides of lysosomal enzyme, which are essential for lysosomal enzyme-targeted trafficking.
Molecular pathology
GNPTG mutations are linked to mucolipidosis IIIC.

单词	gnptg
释义	GNPTG GNPTG A gene on chromosome 16p13.3 that encodes the gamma subunit of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of 2 alpha, 2 beta and 2 gamma subunits. In the Golgi apparatus, GNPTG catalyses the first step in the synthesis of mannose 6-phosphate recognition markers on oligosaccharides of lysosomal enzyme, which are essential for lysosomal enzyme-targeted trafficking. Molecular pathology GNPTG mutations are linked to mucolipidosis IIIC.
随便看	idgah idgara idgarb idgas id-gb idgb idgc idgca idgcc idgdm idge idgec idgf idgi idgis idgo idgp idgr idgra id grinding idgrt idgs idgt idgte idgu