| 单词 |
gemcitabine |
| 释义 |
gemcitabine
gem·cit·a·bine G5075233 (jĕm-sī′tə-bēn′) n. A nucleoside analog, C9H11F2N3O4, used in its hydrochloride form in the treatment of pancreatic cancer and in combination with other drugs to treat breast, ovarian, and non-small cell lung cancer.
[gem-, perhaps shortening and alteration of CCRF-CEM, designation of the leukemia cell culture on which it was first tested + -citabine, nucleoside analog antiviral and anticancer drug suffix; see zalcitabine.] gemcitabine
gemcitabine [jem-sit´ah-bēn] an antineoplastic agent used in chemotherapy for pancreatic adenocarcinoma and carcinoma" >non–small cell lung carcinoma; administered by intravenous infusion as the hydrochloride salt.gemcitabine Gemzar™ Oncology An IV antimetabolic antineoplastic used with cisplatin for inoperable non-small cell lung CA, and as a single agent for inoperable pancreas CA Side effects ↓ WBCs and platelets; ↑ liver enzymes; 10% discontinued medication due to flu-like Sx, N&V, rash. See Cisplatin. Cf 5-FU. gemcitabine A CYTOTOXIC anticancer drug. A brand name is Gemzar. |
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