gemcitabine

gem·cit·a·bine

G5075233 (jĕm-sī′tə-bēn′) n. A nucleoside analog, C₉H₁₁F₂N₃O₄, used in its hydrochloride form in the treatment of pancreatic cancer and in combination with other drugs to treat breast, ovarian, and non-small cell lung cancer.

[gem-, perhaps shortening and alteration of CCRF-CEM, designation of the leukemia cell culture on which it was first tested + -citabine, nucleoside analog antiviral and anticancer drug suffix; see zalcitabine.]

gemcitabine

[jem-sit´ah-bēn] an antineoplastic agent used in chemotherapy for pancreatic adenocarcinoma and carcinoma" >non–small cell lung carcinoma; administered by intravenous infusion as the hydrochloride salt.

gemcitabine

Gemzar^™ Oncology An IV antimetabolic antineoplastic used with cisplatin for inoperable non-small cell lung CA, and as a single agent for inoperable pancreas CA Side effects ↓ WBCs and platelets; ↑ liver enzymes; 10% discontinued medication due to flu-like Sx, N&V, rash. See Cisplatin. Cf 5-FU.

gemcitabine

A CYTOTOXIC anticancer drug. A brand name is Gemzar.

单词	gemcitabine
释义	gemcitabine gem·cit·a·bine G5075233 (jĕm-sī′tə-bēn′) n. A nucleoside analog, C₉H₁₁F₂N₃O₄, used in its hydrochloride form in the treatment of pancreatic cancer and in combination with other drugs to treat breast, ovarian, and non-small cell lung cancer. [`gem-`, perhaps shortening and alteration of `CCRF-CEM`, designation of the leukemia cell culture on which it was first tested + `-citabine`, nucleoside analog antiviral and anticancer drug suffix; see zalcitabine.] gemcitabine gemcitabine [jem-sit´ah-bēn] an antineoplastic agent used in chemotherapy for pancreatic adenocarcinoma and carcinoma" >non–small cell lung carcinoma; administered by intravenous infusion as the hydrochloride salt. gemcitabine Gemzar^™ Oncology An IV antimetabolic antineoplastic used with cisplatin for inoperable non-small cell lung CA, and as a single agent for inoperable pancreas CA Side effects ↓ WBCs and platelets; ↑ liver enzymes; 10% discontinued medication due to flu-like Sx, N&V, rash. See Cisplatin. Cf 5-FU. gemcitabine A CYTOTOXIC anticancer drug. A brand name is Gemzar.
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