fusin

enUK

fu·sin

(fyū'zin), A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]

CXCR4

A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which binds specifically to stromal cell-derived factor-1, transducing a signal by increasing intracellular calcium ions and enhancing MAPK1/MAPK3 activation. It acts as a receptor for extracellular ubiquitin, is involved in haematopoiesis and in cardiac ventricular septum formation, plays a role in gastrointestinal tract vascularisation by regulating vascular branching and/or remodelling in endothelial cells, may be involved in cerebellar development and, in the CNS, may mediate hippocampal-neuron survival.
Molecular pathology
CXCR4 acts with the CD4 to support HIV entry into cells; it is highly expressed in breast cancer cells. CXCR4 mutations cause WHIM (warts, hypogammaglobulinaemia, infections, and myelokathexis) syndrome.

fu·sin

(fyū'zin) A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]

单词	fusin
释义	DictionarySeeFuxin fusin enUK fu·sin (fyū'zin), A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in] CXCR4 A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which binds specifically to stromal cell-derived factor-1, transducing a signal by increasing intracellular calcium ions and enhancing MAPK1/MAPK3 activation. It acts as a receptor for extracellular ubiquitin, is involved in haematopoiesis and in cardiac ventricular septum formation, plays a role in gastrointestinal tract vascularisation by regulating vascular branching and/or remodelling in endothelial cells, may be involved in cerebellar development and, in the CNS, may mediate hippocampal-neuron survival. Molecular pathology CXCR4 acts with the CD4 to support HIV entry into cells; it is highly expressed in breast cancer cells. CXCR4 mutations cause WHIM (warts, hypogammaglobulinaemia, infections, and myelokathexis) syndrome. fu·sin (fyū'zin) A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]
随便看	national association of county administrators national association of county agricultural agents national association of county and city health national association of county and city health officials national association of county behavioral health directors national association of county engineers national association of county health officials national association of county human services administrators national association of county park & recreation officials national association of county planners national association of county veterans service officers national association of credit management national association of credit union chairmen national association of credit union workers national association of cruise-oriented agencies national association of dealers in ancient, oriental and primitive art national association of deans and advisers of men national association of decorative fabric distributors national association of desktop publishers national association of development companies national association of diesel motorsports national association of diocesan ecumenical officers national association of direct offering specialist national association of directors of nursing administration national association of dive rescue specialists