fusin

enUK

fu·sin

(fyū'zin), A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]

CXCR4

A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which binds specifically to stromal cell-derived factor-1, transducing a signal by increasing intracellular calcium ions and enhancing MAPK1/MAPK3 activation. It acts as a receptor for extracellular ubiquitin, is involved in haematopoiesis and in cardiac ventricular septum formation, plays a role in gastrointestinal tract vascularisation by regulating vascular branching and/or remodelling in endothelial cells, may be involved in cerebellar development and, in the CNS, may mediate hippocampal-neuron survival.
Molecular pathology
CXCR4 acts with the CD4 to support HIV entry into cells; it is highly expressed in breast cancer cells. CXCR4 mutations cause WHIM (warts, hypogammaglobulinaemia, infections, and myelokathexis) syndrome.

fu·sin

(fyū'zin) A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]

单词	fusin
释义	DictionarySeeFuxin fusin enUK fu·sin (fyū'zin), A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in] CXCR4 A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which binds specifically to stromal cell-derived factor-1, transducing a signal by increasing intracellular calcium ions and enhancing MAPK1/MAPK3 activation. It acts as a receptor for extracellular ubiquitin, is involved in haematopoiesis and in cardiac ventricular septum formation, plays a role in gastrointestinal tract vascularisation by regulating vascular branching and/or remodelling in endothelial cells, may be involved in cerebellar development and, in the CNS, may mediate hippocampal-neuron survival. Molecular pathology CXCR4 acts with the CD4 to support HIV entry into cells; it is highly expressed in breast cancer cells. CXCR4 mutations cause WHIM (warts, hypogammaglobulinaemia, infections, and myelokathexis) syndrome. fu·sin (fyū'zin) A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell. [fuse, fr. L. fundo, pp. fusum, to melt, + -in]
随便看	rylke, stanislav danilovich rylosol rylov, arkadii rylov, arkadii aleksandrovich rylp rylsk rylskii, iakov rylskii, iakov anufrievich rylskii, maksim rylskii, maksim fadeevich rym ryman, robert ryman, robert tracy rymarenko, sergei rymarenko, sergei stepanovich ryme seventieths seven tongues of fire seven transmembrane domain orphan receptor seven transmembrane helix receptor seven-transmembrane helix receptor seven transmembrane receptor bltr2 seven-transmembrane receptor, lymphocyte, 22 seven-transmembrane-segment receptor, spleen seventy