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glomerulosclerosis Translationsglomerulosclerosis
glomerulosclerosis[glə¦mər·yə·lō·sklə¦rō·səs] (medicine) Fibrosis of the renal glomeruli. glomerulosclerosis
glomerulosclerosis [glo-mer″u-lo-sklĕ-ro´sis] arteriolar nephrosclerosis.diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome" >nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.glo·mer·u·lo·scle·ro·sis (glō-mer'yū-lō-sklē-rō'sis), Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes. Synonym(s): glomerular sclerosis [glomerulus + G. sklērōsis, hardness] glomerulosclerosis Nephrology A degenerative lesion of the renal glomeruli caused by ASHD or DM. See Kimmelsteil-Wilson disease. glo·mer·u·lo·scle·ro·sis (glō-mer'yū-lō-skler-ō'sis) Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes mellitus. [glomerulus + G. sklērōsis, hardness]glomerulosclerosis A kidney disease in which many glomeruli (see GLOMERULUS), previously damaged by inadequate blood supply or GLOMERULONEPHRITIS, become replaced by a non-functioning glassy (hyaline) material. It sometimes occurs without prior damage. The effects resemble those of the NEPHROTIC SYNDROME and kidney function gradually deteriorates. Kidney failure is a common outcome.AcronymsSeegame show |