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单词 gdnf
释义 DictionarySeeATF

GDNF


GDNF

A locus on chromosome 5p13.1-p12 that encodes glial-cell-derived neurotrophic factor, which enhances survival and morphological differentiation of dopaminergic neurons and increases high-affinity dopamine uptake. It is a ligand for the product of the RET (rearranged during transfection) proto-oncogene.
Molecular pathology
GDNF mutations may be associated with Hirschsprung disease.

GDNF


AcronymDefinition
GDNFGlial-Cell Line-Derived Neurotrophic Factor (aka Glia Derived Neurotrophic Factor)
GDNFGesinnungsgemeinschaft der Neue Front (German)
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