Genotypic Environment

(genotypic background), the sum total of the genes exerting an influence on the expression of a given gene in the phenotype (the structures and functions of the organism). The term was introduced by the Soviet geneticist S. S. Chetverikov in 1926. Subsequently, it was experimentally established that the expression of each gene depends on the influence of other genes, In particular, this is proved by the existence of gene-regulators. With the intensification of research on the cell as an integral system, the role of the genotypic environment is proving to be of ever greater significance, above all in the interdependent processes of metabolism.