Gilbert disease

[zhēl-bār´] 1. hyperbilirubinemia I.2. a relatively common, hereditary, benign or subclinical form of hyperbilirubinemia caused by reduced rates of hepatic uptake and conjugation of bilirubin. Patients may have mild, intermittent jaundice, fatigue, and weakness. Although the disease is present from birth, it usually presents clinically in the second or third decade of life. No treatment is necessary and the prognosis is excellent. Called also Gilbert syndrome and hyperbilirubinemia I.

Gilbert syndrome

A benign hereditary condition (OMIM:143500) in which reduced bilirubin transferase activity results in intermittent hyperbilirubinaemia.

fa·mil·i·al non·he·mo·lyt·ic jaun·dice

(fă-mil'ē-ăl non'hē-mō-lit'ik jawn'dis) Mild form of the hepatic disorder due to increased amounts of unconjugated bilirubin in the plasma without evidence of liver damage, biliary obstruction, or hemolysis; thought to be due to an inborn error of metabolism in which the excretion of bilirubin by the liver is defective.
Synonym(s): Gilbert disease.

Gilbert,

Nicholas A., French physician, 1858-1927. Gilbert disease - Synonym(s): familial nonhemolytic jaundiceGilbert syndrome - Synonym(s): familial nonhemolytic jaundice

单词	gilbert disease
释义	DictionarySeedisease Gilbert disease Gilbert disease [zhēl-bār´] 1. hyperbilirubinemia I.2. a relatively common, hereditary, benign or subclinical form of hyperbilirubinemia caused by reduced rates of hepatic uptake and conjugation of bilirubin. Patients may have mild, intermittent jaundice, fatigue, and weakness. Although the disease is present from birth, it usually presents clinically in the second or third decade of life. No treatment is necessary and the prognosis is excellent. Called also Gilbert syndrome and hyperbilirubinemia I. Gilbert syndrome A benign hereditary condition (OMIM:143500) in which reduced bilirubin transferase activity results in intermittent hyperbilirubinaemia. fa·mil·i·al non·he·mo·lyt·ic jaun·dice (fă-mil'ē-ăl non'hē-mō-lit'ik jawn'dis) Mild form of the hepatic disorder due to increased amounts of unconjugated bilirubin in the plasma without evidence of liver damage, biliary obstruction, or hemolysis; thought to be due to an inborn error of metabolism in which the excretion of bilirubin by the liver is defective. Synonym(s): Gilbert disease. Gilbert, Nicholas A., French physician, 1858-1927. Gilbert disease - Synonym(s): familial nonhemolytic jaundiceGilbert syndrome - Synonym(s): familial nonhemolytic jaundice
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