glutamine synthetase

glu·ta·mine syn·the·tase

an enzyme that catalyzes the reaction of l-glutamate, ammonia, and ATP to glutamine, ADP, and orthophosphate; one of the few known mammalian enzymes that uses ammonium ion as a substrate under physiologic conditions.

GLUL

An intronless gene on chromosome 1q31 that encodes a glutamine synthetase, which catalyses the synthesis of glutamine from glutamate and ammonia. Glutamine is a key source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signalling. GLUL is expressed during early foetal stages, and plays an important role in controlling pH by removing ammonia from circulation.
Molecular pathology
GLUL mutations are associated with congenital glutamine deficiency.

单词	glutamine synthetase
释义	DictionarySeeglutamine glutamine synthetase glutamine synthetase [′glüd·ə‚mēn ′sin·thə‚tās] (biochemistry) An enzyme which catalyzes the formation of glutamine from glutamic acid and ammonia, using adenosine triphosphate as a source of energy. glutamine synthetase glu·ta·mine syn·the·tase an enzyme that catalyzes the reaction of l-glutamate, ammonia, and ATP to glutamine, ADP, and orthophosphate; one of the few known mammalian enzymes that uses ammonium ion as a substrate under physiologic conditions. GLUL An intronless gene on chromosome 1q31 that encodes a glutamine synthetase, which catalyses the synthesis of glutamine from glutamate and ammonia. Glutamine is a key source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signalling. GLUL is expressed during early foetal stages, and plays an important role in controlling pH by removing ammonia from circulation. Molecular pathology GLUL mutations are associated with congenital glutamine deficiency. AcronymsSeeGS
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