glutamic acid decarboxylase


glutamic acid decarboxylase

Abbreviation: GAD
An enzyme (molecular mass 65 kD) that is found in the brain and the islet cells of the pancreas and participates in the synthesis of gamma-aminobutyric acid. Antibodies to GAD are found in the blood of patients with diabetes mellitus, type, and stiff-person syndrome. See also: decarboxylase