glutamate decarboxylase

glu·ta·mate de·car·box·yl·ase (GAD),

a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO₂ as well as l-aspartate to 3-aminopropanoate and CO₂; a defect in the binding of this protein's coenzyme is believed to cause pyridoxine dependency with seizures. Synonym(s): aspartate 1-decarboxylase

GLUL

An intronless gene on chromosome 1q31 that encodes a glutamine synthetase, which catalyses the synthesis of glutamine from glutamate and ammonia. Glutamine is a key source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signalling. GLUL is expressed during early foetal stages, and plays an important role in controlling pH by removing ammonia from circulation.
Molecular pathology
GLUL mutations are associated with congenital glutamine deficiency.

单词	glutamate decarboxylase
释义	glutamate decarboxylase glu·ta·mate de·car·box·yl·ase (GAD), a carboxy-lyase converting l-glutamate to 4-aminobutyrate and CO₂ as well as l-aspartate to 3-aminopropanoate and CO₂; a defect in the binding of this protein's coenzyme is believed to cause pyridoxine dependency with seizures. Synonym(s): aspartate 1-decarboxylase GLUL An intronless gene on chromosome 1q31 that encodes a glutamine synthetase, which catalyses the synthesis of glutamine from glutamate and ammonia. Glutamine is a key source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signalling. GLUL is expressed during early foetal stages, and plays an important role in controlling pH by removing ammonia from circulation. Molecular pathology GLUL mutations are associated with congenital glutamine deficiency.
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