acute panmyelosis with myelofibrosis

acute panmyelosis with myelofibrosis

An aggressive form of acute myeloid leukaemia, in which the bone marrow is seriously damaged due to either a clonal expansion or toxic exposure, resulting in pancytopenia and poor prognosis (median survival post-diagnosis: 9 months).

acute panmyelosis with myelofibrosis

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APMF

A form of acute leukemia in which multiple cell lines develop aberrantly, infiltrate internal organs, e.g., the spleen, and cause extensive bone marrow fibrosis.