Gaucher cells

Gauch·er cells

(gō-shā'), large, finely and uniformly vacuolated cells derived from the reticuloendothelial system, and found especially in the spleen, lymph nodes, liver, and bone marrow of patients with Gaucher disease; Gaucher cells contain kerasin (a cerebroside), which accumulates as a result of a genetically determined absence of the enzyme glucosylceramidase.

Gauch·er cells

(gō-shā' selz) Large, finely, and uniformly vacuolated cells derived from the reticuloendothelial system and found especially in the spleen, lymph nodes, liver, and bone marrow of patients with Gaucher disease; contain kerasin (a cerebroside), which accumulates as a result of a genetically determined absence of the enzyme glucosylceramidase.

Gaucher,

Philippe Charles Ernest, French physician, 1854-1918. Gaucher cells - large, finely and uniformly vacuolated cells derived from the reticuloendothelial system and found especially in the spleen, lymph nodes, liver, and bone marrow of patients with Gaucher disease.Gaucher disease - a lysosomal storage disease. Synonym(s): cerebroside lipidosis; familial splenic anemiaGaucher type of histiocytepseudo-Gaucher cell - a plasma cell, microscopically resembling a Gaucher cell, found in the bone marrow in some cases of multiple myeloma.