giant peristaltic contraction

A prolonged, high-amplitude forward propagating contraction that represents a heightened peristaltic contraction. Giant peristaltic contractions may be induced by cholera toxin, occur in patients with irritable bowel syndrome, and be identical to the migrating action potential complex

giant peristaltic contraction

GI disease A prolonged, high-amplitude forward propagating contraction that represents a heightened peristaltic contraction; GPCs may be induced by cholera toxin, are present in Pts with irritable bowel syndrome, and identical in nature to the migrating action potential complex. Cf Local reflex peristalsis.