单词 | giant cell |
释义 | giant cellgiant cellgiant cellgi·ant cellgiant cellAny markedly enlarged cell seen in benign or malignant lesions; although GCs are highly nonspecific, their presence in the proper setting supports the diagnosis of certain diseases; the epithelioid GCs of Langerhans and Touton are associated with infections and other 'benign' processes–eg, sarcoidosis, have abundant cytoplasm and a rim or clutch of enlarged histiocyte-like nuclei; GCs in tumors are less inhibited by rules of cytologic etiquette and are anointed with adjectival modifiers–eg, bizarre, monster, osteoclastoma-like, Reed-Sternberg; the cell may be markedly enlarged and mitotically active.gi·ant cell(jī'ănt sel)giant cellA large multinucleate cell formed from the fusion of many MACROPHAGES. Giant cells are often a feature of granulomas.gi·ant cell(jī'ănt sel) |
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