释义 |
DictionarySeespotcafe au lait spots
ca·fé au lait spotspigmented cutaneous lesions, ranging from light to dark brown, and due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes; café au lait spots are one of the major cutaneous manifestations of neurofibromatosis (von Recklinghausen disease); six or more café au lait spots, some exceeding 1.5 cm in diameter, can almost always be found in type 1 (peripheral) neurofibromatosis. These are often accompanied by frecklelike spots in the axilla.ca·fé au lait spots (kăf-ā-ō-lā spotz) Pigmented cutaneous lesions, ranging from light to dark brown; due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes. cafe au lait spots Milk coffee-coloured oval patches, from one to 15cm or more long, on the skin. If more than five of these occur in childhood, and especially if they extend into the armpit, it is likely that the condition of NEUROFIBROMATOSIS (Recklinghausen's disease) is developing. |